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Chapter 08 Video 1: Iliac Crest Bone Graft Mechanism

December 22, 2016

Contributors: Wellington K Hsu, MD

Why is it important to remember these components, may you ask? The answer is to contrast the mechanisms of bony healing behind different bone graft options. It is important to remember these components when considering the contrast between mechanisms of bony healing behind different bone graft options. For example, when iliac crest bone graft is placed in the appropriate fusion bed, Bone graft solution involves : Osteoinduction – as in growth factors/cytokines; Osteoconduction – the ideal scaffold in which osteoid is laid down and bone is built; Responding cells – which are abundant with ICBG not only because of the MSCs provided within the graft, but also through a paracrine effect where cells are recruited to the area; Vascular supply – which is the long-term solution for bone repair

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