Dupuytren's Disease


Since its earliest description more than 200 years ago, Dupuytren's disease has fascinated clinicians and basic scientists. Population studies have shown that the prevalence of Dupuytren's disease is influenced by four factors: age, gender, geography, and ethnicity. The nodule and cord are the quintessential pathologic findings in Dupuytren's disease. In the classic scenario of typical disease, the condition is ushered by skin changes, nodule formation, cord formation, disease progression, maturation and contracture, and progressive digital flexion deformity.

Historical perspectives on the disease, pathophysiology, clinical diagnosis, and nonsurgical and surgical treatment of Dupuytren's Disease are reviewed in detail in this OKO article.

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