Diagnosis and Management of Complex Regional Pain Syndrome I and II

Abstract

Complex regional pain syndrome (CRPS) is a chronic neuropathic pain syndrome that primarily affects the extremities, with sprains and fractures being the most common inciting events. CRPS type I, previously known as reflex sympathetic dystrophy, is characterized by the absence of a distinct nerve injury, whereas type II, once referred to as causalgia, occurs after an illness or injury in which there was a documented nerve injury. The past few decades have seen an evolution and an improvement in our understanding of the pathophysiology and treatment of CRPS. Diagnosis is based on clinical findings, and treatment remains a challenge. An interdisciplinary approach, with use of pharmacotherapy and interventional modalities coordinated with psychological and physical therapies, provides the best outcome.

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